Severe itching, especially on the palms of your hands and soles of your feet, and that is more intense at night, can be a sign of obstetric cholestasis (OC), which is also known as intrahepatic cholestasis of pregnancy (ICP). This is a rare liver condition and it occurs more often in women of Indian or Pakistani origin. OC occurs when bile created by the liver doesn’t flow properly into the intestines, possibly due to hormonal changes.
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